The knowledge-based Toxtree expert system (SAR approach) was integrated with the statistically based counter propagation artificial neural network (CP ANN) model (QSAR approach) to contribute to a better mechanistic understanding of a carcinogenicity model for non-congeneric chemicals using Dragon descriptors and carcinogenic potency for rats as Fo
Abstract Background CHD5 is a conventional tumour-suppressing gene in many tumours.The aim of this study was to determine whether CHD5 variants contribute to the risk of hepatocellular carcinoma (HCC).Methods Gene variants were identified using next-generation sequencing targeted on referenced mutations followed by TaqMan genotyping in two case-con
Background: Disaster victim identification (DVI) is a process of identifying the victim who died due to the disaster.Deaths due to disasters can be classified as victims of open disasters and victims of closed disasters.In the open disasters the process of identification is more difficult.Based on regulation of law in Indonesia, the identification
The relative insufficiency of insulin secretion and/or insulin action causes diabetes.However, obesity and type 2 diabetes mellitus can be associated with an absolute increase in circulating insulin, a state known as Rangehood Lampholder hyperinsulinemia.Studies are beginning to elucidate the cause-effect relationships between hyperinsulinemia and
RECOVER is a site-specific decision support system that automatically brings together in a single analysis environment the information necessary for post-fire rehabilitation decision-making.After a major wildfire, law requires that the federal land management agencies certify a comprehensive plan for public safety, burned area stabilization, resour